Diclofenac: An Update on its Mechanism of Action and Safety Profile

Authors: Maryam Saleh Fallatah

Country: Saudi Arabia

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Abstract: Diclofenac is a widely used nonsteroidal anti-inflammatory drug (NSAID) that is prescribed for the treatment of inflammatory conditions such as arthritis, gout, and muscle pain. Despite its effectiveness in managing pain and inflammation, diclofenac has been associated with several safety concerns, including gastrointestinal ulcers, cardiovascular events, and kidney damage. This paper provides an update on the mechanism of action of diclofenac and its safety profile, with a focus on recent research findings. The methods used to gather information for this review included a comprehensive literature search of reputable journals. The results of this review reveal the complex mechanism of action of diclofenac, which involves inhibition of cyclooxygenase enzymes and modulation of inflammatory pathways. The discussion section highlights the safety concerns associated with dicfenac use and provides recommendations for healthcare providers to minimize the risks for patients. In conclusion, diclofenac remains a valuable treatment option for inflammatory conditions, but its use should be carefully monitored to ensure patient safety.

Keywords: Diclofenac, Safety Profile, Nonsteroidal Anti-inflammatory Drugs

Paper Id: 1725

Published On: 2016-02-04

Published In: Volume 4, Issue 1, January-February 2016

Cite This: Diclofenac: An Update on its Mechanism of Action and Safety Profile - Maryam Saleh Fallatah - IJIRMPS Volume 4, Issue 1, January-February 2016.

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