Impact of Postural Drainage Techniques on Mucociliary Clearance and Lung Function in Patients with Cystic Fibrosis: A Quantitative Analysis

Authors: Mohammed Meqbel Alanazi, Amal Abdulaziz bin yaesh

DOI: https://doi.org/10.5281/zenodo.13291447

Short DOI: https://doi.org/gt6q3h

Country: Saudi Arabia

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Abstract: Background: Effective mucociliary clearance is crucial for cystic fibrosis (CF) management. Postural drainage techniques are commonly used to enhance this clearance, but their comparative effectiveness remains uncertain.

Objective: This study aimed to evaluate and compare the impact of Chest Physiotherapy (CPT), Positive Expiratory Pressure (PEP) Therapy, and High-Frequency Chest Wall Oscillation (HFCWO) on mucociliary clearance and lung function in CF patients.

Methods: In a 12-week randomized controlled trial, 30 CF patients were assigned to one of three intervention groups: CPT, PEP, or HFCWO. Outcomes measured included sputum production, lung function (FEV1 and FVC), quality of life (CFQ-R), and frequency of respiratory exacerbations. Data were analyzed using repeated measures ANOVA and other statistical methods.

Results: All techniques resulted in improvements in mucociliary clearance and lung function, with no significant differences observed between groups. Quality of life scores and the frequency of respiratory exacerbations were also similar across interventions.

Conclusion: CPT, PEP, and HFCWO are effective in improving mucociliary clearance and lung function in CF patients, with no single technique demonstrating superior effectiveness. Personalized treatment approaches based on patient preferences may optimize management.

Keywords: cystic fibrosis, mucociliary clearance, postural drainage, chest physiotherapy, positive expiratory pressure, high-frequency chest wall oscillation.

Paper Id: 230969

Published On: 2021-06-03

Published In: Volume 9, Issue 3, May-June 2021

Cite This: Impact of Postural Drainage Techniques on Mucociliary Clearance and Lung Function in Patients with Cystic Fibrosis: A Quantitative Analysis - Mohammed Meqbel Alanazi, Amal Abdulaziz bin yaesh - IJIRMPS Volume 9, Issue 3, May-June 2021. DOI 10.5281/zenodo.13291447

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