The Role of Biochemistry in Personalized Medicine: A Hospital-Based Study on Tailoring Treatment Plans for Chronic Diseases
Authors: Ali S. Alamri, Amal M. Hariri, Alwaleed M. Almalki, Mshary A. Aldraihim, Samar A. Aldugeshem
DOI: https://doi.org/10.5281/zenodo.13627534
Short DOI: https://doi.org/gt878s
Country: Saudi Arabia
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Abstract:
Background: Biochemical analysis plays a crucial role in personalizing treatment for chronic diseases such as diabetes and cancer. This study investigates the impact of biochemical markers on treatment adjustments and patient outcomes in a hospital setting.
Methods: A total of 200 patients were included, with 100 each suffering from diabetes and cancer. Biochemical markers (HbA1c, C-peptide, HER2, EGFR mutations) were monitored at baseline, 24 hours, and 3 months post-treatment. Clinical outcomes and treatment modifications based on these markers were assessed.
Results: For diabetes patients, personalized treatment led to a significant reduction in HbA1c (1.0%) and improvements in lipid profiles. In cancer patients, treatment adjustments based on HER2 and EGFR levels resulted in improved progression-free survival and overall survival rates. Treatment modifications were made for 32% of diabetes patients and 28% of cancer patients.
Conclusion: Biochemical analysis significantly influences personalized treatment plans, leading to improved management and outcomes for chronic disease patients. Integrating biochemical markers into clinical decision-making enhances therapeutic efficacy and patient care.
Keywords: Biochemical analysis, personalized medicine, diabetes, cancer, HbA1c, HER2, EGFR, treatment outcomes
Paper Id: 231105
Published On: 2022-05-04
Published In: Volume 10, Issue 3, May-June 2022
Cite This: The Role of Biochemistry in Personalized Medicine: A Hospital-Based Study on Tailoring Treatment Plans for Chronic Diseases - Ali S. Alamri, Amal M. Hariri, Alwaleed M. Almalki, Mshary A. Aldraihim, Samar A. Aldugeshem - IJIRMPS Volume 10, Issue 3, May-June 2022. DOI 10.5281/zenodo.13627534