Multidisciplinary Approaches to Managing Osteoarthritis: Integrating Imaging, Laboratory Markers, Pharmacological Interventions, and Physical Therapy for Optimal Patient Outcomes

Authors: Sultan K. Alshammari, Eman Q. Almutairi, Rehab S. Alsunaidi, Ruba K. Alhammad, Aminah K. Alanazi, Maryam H. Aldossari, Zahra A. Asiri, Husam A. Altahan, Fahad Alenizy

DOI: https://doi.org/10.5281/zenodo.13902051

Short DOI: https://doi.org/g7k935

Country: Saudi Arabia

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Abstract: Background: Osteoarthritis (OA) is a degenerative joint disease that requires comprehensive management to improve patient outcomes. This study investigates the effectiveness of a multidisciplinary approach integrating imaging, laboratory markers, pharmacological interventions, and physical therapy in managing OA progression and improving patient outcomes.

Methods: A retrospective cohort study was conducted in a tertiary hospital, including 250 patients diagnosed with knee or hip OA. Imaging (X-rays, MRI), laboratory markers (CRP, ESR), pharmacological treatments (NSAIDs, corticosteroid injections), and physical therapy were analyzed over 12 months to assess their impact on pain, joint mobility, and functional outcomes.

Results: Imaging showed significant joint space narrowing and cartilage degradation over 12 months. Elevated CRP and ESR were modestly correlated with disease severity. Combination pharmacotherapy (NSAIDs + corticosteroid injections) yielded the highest pain reduction and functional improvement. Physical therapy, when combined with pharmacotherapy, resulted in a 60% improvement in joint mobility and a 45% improvement in WOMAC scores.

Conclusion: A multidisciplinary approach integrating imaging, laboratory markers, pharmacotherapy, and physical therapy significantly improves pain, mobility, and function in OA patients, supporting the need for comprehensive, personalized care.

Keywords: Osteoarthritis, multidisciplinary approach, imaging, laboratory markers, pharmacological interventions, physical therapy, joint space narrowing, functional outcomes.

Paper Id: 231305

Published On: 2020-06-03

Published In: Volume 8, Issue 3, May-June 2020

Cite This: Multidisciplinary Approaches to Managing Osteoarthritis: Integrating Imaging, Laboratory Markers, Pharmacological Interventions, and Physical Therapy for Optimal Patient Outcomes - Sultan K. Alshammari, Eman Q. Almutairi, Rehab S. Alsunaidi, Ruba K. Alhammad, Aminah K. Alanazi, Maryam H. Aldossari, Zahra A. Asiri, Husam A. Altahan, Fahad Alenizy - IJIRMPS Volume 8, Issue 3, May-June 2020. DOI 10.5281/zenodo.13902051

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