Strategies for Treating Dysphagia in Critically Ill Patients Using Biomarker Envisaged Approaches.

Authors: Nouf S. Almulaik, Manal A. Alkhunaizan, Ali E. Alanazi, Tariq I. Almalki, Majed A. Alzahrani, Mohammed A. Shujaa, Yasser B. Alsowailem, Abdullah M. Alboaimi

DOI: https://doi.org/10.5281/zenodo.14043623

Short DOI: https://doi.org/g8p78j

Country: Saudi Arabia

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Abstract: Background: Dysphagia considerably makes recovery over the angry and makes them more prone to aspiration pneumonia, and lengthy duration of hospital stay. It is the objective of this study to identify the effectiveness of intervention in the form of biomarker’s to manage dysphagia in critically ill patients.

Methods: One hundred twenty critically ill patients diagnosed with dysphagia were enrolled in a prospective cohort study at a tertiary referral hospital. C-reactive protein (CRP), serum albumin, and creatine kinase (CK) were evaluated upon admission and every 2 days whenever feasible until hospital discharge or for a maximum of 14 days. Measurement of Clinical Swallowing Evaluation and Videofluoroscopic Swallow Study (VFSS) was made on bi-weekly intervals and management was done depending on pathological biomarker levels.

Results: The swallowing function improved with improvement of CRP levels (r = -0.62, p = 0.001) and improvement in the albumin levels (r = 0.59, p = 0.002). Cycles of CK levels have weak correlation to swallowing function improvement response (r = -0.31, p = 0.05). Age, disease gravities, duration of the disease process and Chronic medicinal history are also risk factors. Patients with chronic illnesses and dysphagia showed marked improvement in swallowing function and marked decrease in dysphagia associated complications who had better control of inflammatory and nutritional diseases.

Conclusions: With the help of biomarkers, the management of dysphagia in critical care patients can be further enhanced. Utilizing CRP and albumin can be useful in assessing inflammation and nutrition to help guide treatment decisions and their application to the patients’ recovery.

Keywords: Dysphagia, Critical Care, Biomarkers, C-reactive Protein, Albumin, Swallowing Disorders, Intensive Care.

Paper Id: 231521

Published On: 2021-01-09

Published In: Volume 9, Issue 1, January-February 2021

Cite This: Strategies for Treating Dysphagia in Critically Ill Patients Using Biomarker Envisaged Approaches. - Nouf S. Almulaik, Manal A. Alkhunaizan, Ali E. Alanazi, Tariq I. Almalki, Majed A. Alzahrani, Mohammed A. Shujaa, Yasser B. Alsowailem, Abdullah M. Alboaimi - IJIRMPS Volume 9, Issue 1, January-February 2021. DOI 10.5281/zenodo.14043623

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