Assessing the Impact of Inflammatory Biological Markers and Nutrition on Chronic Diseases

Authors: Hani M.Alenezi, Ali E.Alanazi, Faisal F. Almutairi, Ghadah A. Alahmari, Tariq I. Almalki, Mohammed A. Shujaa, Dana A. Almishri, Amaal M. Alzahrani, Saeed J. Alghamdi, Abdulaziz S. Almasabi, Redha M. Alanazi

DOI: https://doi.org/10.5281/zenodo.14043663

Short DOI: https://doi.org/g8p78x

Country: Saudi Arabia

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Abstract: Background: Chronic diseases include cardiovascular diseases, type 2 diabetes, and chronic obstructive pulmonary disease (COPD), which are among the top contributors of morbidity and mortality in most parts of the world. The increasing number of studies indicates that inflammation caused by foods can aggravate the progress of such chronic diseases.

Objective: This study aimed to assess the associations between dietary habits, presence of inflammatory biomarkers, and chronic diseases among adults seeking for care at a tertiary health facility.

Methods: This was a cross sectional study where 500 (five hundred) adults from [Hospital Name] were examined. A recall 24 hour dietary history using a validated food frequency questionnaire was employed while serum concentrations of C-reactive protein (CRP), interleukin-6 (IL-6), and tumor necrosis factor-alpha (TNF-α) were quantitatively determined by ELISA. Statistical analysis was primarily based on multivariable regression models to assess the effect of diet on inflammation and its effect on chronic diseases.

Results: Those who practiced a Mediterranean diet had significantly lower values for CRP, IL-6, and TNF-α than participants from the Western diet, with p value < 0.001. Management of elevated inflammatory markers was associated with high odds of ever having cardiovascular and diabetes diseases.

Conclusions: Apart from genetic predisposition chronic diseases can be affected by diet patterns since inflammation profiles are altered by eating patterns. Therefore dietary intervention seems a useful strategy to implement for prevention or management of chronic diseases.

Keywords: Chronic diseases, inflammation, dietary patterns, Mediterranean diet, inflammatory markers, CRP, IL-6, TNF-α.

Paper Id: 231524

Published On: 2024-01-10

Published In: Volume 12, Issue 1, January-February 2024

Cite This: Assessing the Impact of Inflammatory Biological Markers and Nutrition on Chronic Diseases - Hani M.Alenezi, Ali E.Alanazi, Faisal F. Almutairi, Ghadah A. Alahmari, Tariq I. Almalki, Mohammed A. Shujaa, Dana A. Almishri, Amaal M. Alzahrani, Saeed J. Alghamdi, Abdulaziz S. Almasabi, Redha M. Alanazi - IJIRMPS Volume 12, Issue 1, January-February 2024. DOI 10.5281/zenodo.14043663

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