Comparing the Effectiveness of Automated Blood Donation Systems vs. Manual Methods in Maintaining Blood Component Quality: A Quantitative Analysis

Authors: Bayan A. Bafrhan, Manar O. Alanazi, Ali H. Alanazi, Fayha T. Almutairi, Wael A. Almutairi

DOI: https://doi.org/10.5281/zenodo.13853546

Short DOI: https://doi.org/g53rbc

Country: Saudi Arabia

Full-text Research PDF File:   View   |   Download

Abstract: Background: Blood donation methods, whether automated or manual, impact the quality and shelf life of blood components. This study evaluates the effectiveness of automated apheresis systems compared to manual whole blood donation in maintaining the quality of red blood cells (RBCs), platelets, and plasma.

Methods: A quantitative comparative analysis was conducted on 200 blood donors at a tertiary hospital. Donors were randomly assigned to either automated or manual blood donation. Blood component quality was assessed through key parameters such as RBC hemolysis, platelet aggregation, and plasma coagulation factor stability over standardized storage periods.

Results: RBCs collected via automated methods exhibited significantly lower hemolysis levels and better preservation of pH and oxygen-carrying capacity compared to manual methods (p < 0.05). Platelets from automated systems demonstrated higher aggregation responses and counts throughout the 5-day storage period. Plasma collected via automated methods showed greater stability in coagulation factors over 30 days.

Conclusion: Automated blood donation systems maintain superior blood component quality and extend the shelf life of RBCs, platelets, and plasma compared to manual methods. These findings support the broader use of automated systems to enhance blood product safety and efficacy.

Keywords: Automated blood donation, manual blood donation, blood component quality, red blood cells, platelets, plasma, blood storage

Paper Id: 231264

Published On: 2024-06-11

Published In: Volume 12, Issue 3, May-June 2024

Share this